₨1,000.00
Alprostadil is a vasodilator and platelet aggregation inhibitor, prostaglandin e1 (pge1). it belongs to institution of compounds called autacoids (autacoids function as a nearby hormone). chemically Alprostadil is recognized as (11a, 13e, 15s)-eleven, 15-dihydroxy-nine-oxoprost-13-en-1-oic acid. Alprostadil is isolated from the seminal vesicle tissues of sheep. Alprostadil is used for short upkeep of the patent ductus arteriosus until corrective or palliative surgical treatment may be completed in neonates with congenital heart defects. administered intravenously or intra-arterially.
Description
Alprostadil Price In Pakistan
Alprostadil is a vasodilator and platelet aggregation inhibitor, prostaglandin e1 (pge1). it belongs to institution of compounds called autacoids (autacoids function as a nearby hormone). chemically Alprostadil is recognized as (11a, 13e, 15s)-eleven, 15-dihydroxy-nine-oxoprost-13-en-1-oic acid. Alprostadil is isolated from the seminal vesicle tissues of sheep. Alprostadil is used for short upkeep of the patent ductus arteriosus until corrective or palliative surgical treatment may be completed in neonates with congenital heart defects. administered intravenously or intra-arterially.
Description
Alprostadil is a white to off-white crystalline powder with a melting point between 115°c and 116° c. caverject is available as a sterile freeze-dried powder for intracavernosal use in sizes: 20 mcg and forty mcg per vial. while reconstituted as directed with 1 ml of bacteriostatic water for injection preserved with benzyl alcohol zero.945% w/v, gives 1.thirteen ml of reconstituted solution. each ml of caverject carries 20.5 mcg or 41.1 mcg of alprostadil relying on vial energy, 172 mg of lactose, 47 mcg of sodium citrate and 8.four mg of benzyl alcohol. the deliverable quantity of Alprostadil is 20 mcg or 40 mcg consistent with ml because about 0.5 mcg for the 20 mcg strength and 1.1 mcg for the 40 mcg energy is misplaced because of adsorption to the vial and syringe. for the duration of manufacture, the ph of Alprostadil for injection was adjusted with hydrochloric acid and/or sodium hydroxide earlier than lyophilization.
Dosage And Management
Important dosage and management instructions
- Alprostadil is to be had in single-dose vials containing 20 mcg or 40 mcg of Alprostadil. make certain a brand new, accurate electricity vial of caverject is used for each affected person dosage coaching.
- Administration of the primary injections of Alprostadil have to be accomplished in the medical doctor’s office through medically educated employees.
- Cautiously titrate the dose of Alprostadil for every affected person to the bottom powerful dose.
- Teach the patient on proper use and assess that they are nicely educated in the self-injection approach prior to initiation of domestic use. endorse the patient to read and punctiliously comply with the affected person
